Relative Versus Attributable Risk of Breast Cancer from Estrogen Replacement Therapy
نویسندگان
چکیده
منابع مشابه
More about: effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin.
BACKGROUND Hormone replacement therapy (HRT) given as unopposed estrogen replacement therapy (ERT) gained widespread popularity in the United States in the 1960s and 1970s. Recent prescribing practices have favored combination HRT (CHRT), i.e., adding a progestin to estrogen for the entire monthly cycle (continuous combined replacement therapy [CCRT]) or a part of the cycle (sequential estrogen...
متن کاملRe: effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin.
The report by Ross et al. (1) in the February 16, 2000, issue of the Journal concludes that a combination of estrogen and progestin increases the risk of breast cancer over time when compared with estrogen alone. A similar conclusion was recently reported in a paper in the Journal of the American Medical Association by Schairer et al. (2). There is little question that hormone therapy, either e...
متن کاملEstrogen replacement therapy in breast cancer survivors.
OBJECTIVE To determine whether estrogen replacement therapy (ERT) adversely affected outcome of breast cancer survivors. METHOD A prospective descriptive study of all breast cancer survivors who requested ERT because of intractable menopausal symptoms. All patients presented voluntarily as gynecological outpatients and were all given oral continuous opposed ERT: 20 premarin and medroxyprogest...
متن کاملMenopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk.
CONTEXT Whether menopausal hormone replacement therapy using a combined estrogen-progestin regimen increases risk of breast cancer beyond that associated with estrogen alone is unknown. OBJECTIVE To determine whether increases in risk associated with the estrogen-progestin regimen are greater than those associated with estrogen alone. DESIGN Cohort study of follow-up data for 1980-1995 from...
متن کاملEstrogen, estrogen plus progestin therapy, and risk of breast cancer.
Epidemiologic evidence relating use of postmenopausal hormones to risk of breast cancer by nature relies on trends in prescribing practices. Data on the adverse effect of combination estrogen plus progestin used for long durations has only become available over the past decade. Evidence is reviewed relating estrogen alone and estrogen plus progestin to increased risk of breast cancer. Whereas c...
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ژورنال
عنوان ژورنال: Journal of Clinical Endocrinology & Metabolism
سال: 1999
ISSN: 0021-972X
DOI: 10.1210/jc.84.6.1875